Abstract
Monte Carlo simulations were carried out to calculate optimum design parameters of an accelerator based Beam Shaping Assembly (BSA) for Boron Neutron Capture Therapy (BNCT) of Brain Cancer setup. Epithermal beam of neutrons were obtained through moderation fast neutrons from 7Li(p,n) reaction in a high density polyethylene moderator and a graphite reflector. The dimensions of the moderator and the reflector were optimized through optimization of epithermal/fast neutron intensity ratio as a function of geometric parameters of the setup. Results of our calculation showed the capability of our setup to treat the tumor within 4 cm of the head surface. The calculated Peak Therapeutic Ratio for the setup was found to be 2.15. With further improvement in the polyethylene moderator design and brain phantom irradiation-arrangement, the setup capabilities can be improved to reach further deep-seated tumor.
| Original language | English |
|---|---|
| Pages (from-to) | 539-544 |
| Number of pages | 6 |
| Journal | Journal of Radioanalytical and Nuclear Chemistry |
| Volume | 274 |
| Issue number | 3 |
| DOIs | |
| State | Published - Dec 2007 |
Bibliographical note
Funding Information:The authors wish to acknowledge the support of the Physics Department at King Fahd University of Petroleum and Minerals, Dhahran, Saudi Arabia.
ASJC Scopus subject areas
- Analytical Chemistry
- Nuclear Energy and Engineering
- Radiology Nuclear Medicine and imaging
- Pollution
- Spectroscopy
- Public Health, Environmental and Occupational Health
- Health, Toxicology and Mutagenesis
