Design and Experimental Validation of a Noninvasive Glucose Monitoring System Using RF Antenna-Based Biosensor

Yaqub Mahnashi, Khurram Karim Qureshi, Abdullah A. Al-Shehri, Hussein Attia*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

3 Scopus citations


This article presents an end-to-end microwave-based system to detect the glucose level in aqueous solutions through a noninvasive scheme. A microwave signal is generated and transmitted through the sample under test (i.e., glucose-water solution). The received signal is then conditioned using a low-noise amplifier (LNA), a bandpass filter (BPF), and an RF detector. The change in the dc output voltage on the receiver side is used as a new way to detect the glucose level. The proposed glucose sensor is implemented using two RF microstrip patch antennas that resonate at 5.7 GHz and are fabricated using an FR-4 substrate. The design specifications of the sensing antennas are thoroughly studied and presented. The system is verified experimentally using glucose-water testing samples. The experimental results confirm the correlation between the glucose concentration and the dc output voltage for a concentration range of 0-5000 mg/dL. The effect of the transmitted power level on the system performance is also investigated. Finally, the proposed system is compared with the state-of-the-art systems reported in the literature.

Original languageEnglish
Pages (from-to)2856-2864
Number of pages9
JournalIEEE Sensors Journal
Issue number3
StatePublished - 1 Feb 2023

Bibliographical note

Publisher Copyright:
© 2001-2012 IEEE.


  • Biomedical applications
  • biosensors
  • glucose detection using RF sensors
  • noninvasive glucose monitoring

ASJC Scopus subject areas

  • Instrumentation
  • Electrical and Electronic Engineering


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