Crystal structures of dual dopamine D₂ and serotonin 5-HT_1A active arylpiperidinyl-2(1H)-3,4-dihydroquinolinones

8-(1-((5-Cyclopentenylpyridin-3-yl)methyl)piperidin-4-yl)-3,4-dihydroquinolin-2(1H)-one (1) and 8-(1-(3- cyclopentenylbenzyl)piperidin-4-yl)-3,4-dihydroquinolin-2(1H)-one (2) are synthesized and obtained in the crystalline state for X-ray diffraction studies. In the asymmetric unit of compound 1, there are two independent molecules (A and B) having similar conformations. In the crystals of compounds 1 and 2, individual molecules are linked by pairs of N-H•••O hydrogen bonds forming A-A and B-B inversion dimers with R ₂ ² (8) ring motifs. The dimers are stabilized by N-H•••O hydrogen bonds and are linked via C-H•••O short contact interactions, forming a three-dimensional and two-dimensional networks in 1 and 2 respectively. The network in 2 is further stabilized by a number of C-H•••π interactions. Compounds 1 and 2 have a dual dopamine D2 and serotonin 5-HT_1A receptor profile.