TY - JOUR
T1 - Correction
T2 - Valorization of Araucaria Excelsa Extract for Synthesis of Silver Nanoparticles and their Potential Anticancer Properties (Waste and Biomass Valorization, (2025), 10.1007/s12649-025-03418-6)
AU - Javed, Eisha
AU - Zubair, Muhammad
AU - Alghanem, Suliman Mohammed Suliman
AU - Batool, Faiza
AU - Shaheen, Tayyaba
AU - Alhaithloul, Haifa Abdul Aziz Sakit
AU - Niazi, Muhammad Bilal Khan
AU - Rizwan, Muhammad
N1 - Publisher Copyright:
© The Author(s), under exclusive licence to Springer Nature B.V. 2025.
PY - 2025
Y1 - 2025
N2 - In the original version of this article, the abstract was incorrectly published. The incorrect and the corrected version of the abstract are given below. Incorrect version: The current research work deals with the eco-friendly production of silver nanoparticles (AgNPs) using the aqueous leaf extract of Araucaria excelsa. Furthermore, biomedical significance of AgNPs was assessed particularly in the areas of anticancer, antioxidant, and antidiabetic applications. The adoption of this environmentally friendly technique overcomes the disadvantages of traditional chemical synthesis by employing phytochemicals as the natural reducing and stabilizing agents, thus reducing the toxicity and environmental impact to a great extent. The AgNPs obtained through biosynthesis were characterized by a series of techniques like UV–Vis spectroscopy, FTIR spectroscopy, scanning electron microscopy (SEM), and X-ray diffraction (XRD) for their formation, stability, and crystalline morphology. The UV–Vis spectrum showed a strong peak of surface plasmon resonance at 435.24 nm, whereas SEM images showed nanoparticles that were spherical and uniformly dispersed with an average size of 28.32 nm, which is an indication of successful nanoparticle synthesis. Assessments based on biological factors showed that the A. excelsa-derived AgNPs are very effective, having an antioxidant activity of 78.26%, a strong α-glucosidase inhibition of 65.44%, and also impressive cytotoxicity of 73.22% against human MCF-7 breast cancer cells, thus confirming their medicinal properties against stress, diabetes, and cancer spread. The indicated anticancer activities are due to the plant-derived bioactive molecules’ synergistic interaction which leads to an increase in the generation of reactive oxygen species and consequently the death of cancer cells. With this, A. excelsa-mediated AgNPs become the best choice for a nanoplatform that is easy to produce, biocompatible, and also sustainable for biomedical applications. Future studies are needed to clarify anticancer mechanisms at the molecular level, perform in vivo safety evaluations, and also look into the translational prospects of these green-synthesized nanoparticles in targeted cancer therapy and drug delivery. Corrected version: The current research work deals with the eco-friendly method to produce silver nanoparticles (AgNPs) using the aqueous leaf extract of Araucaria excelsa and furthermore, its biomedical significance, particularly in the areas of anticancer, antioxidant, and antidiabetic applications. The adoption of this environmentally friendly technique overcomes the disadvantages of traditional chemical synthesis by employing phytochemicals as the natural reducing and stabilizing agents, thus reducing the toxicity and environmental impact to a great extent. The AgNPs obtained through biosynthesis were characterized by a series of techniques like UV–Vis spectroscopy, FTIR spectroscopy, scanning electron microscopy (SEM), and X-ray diffraction (XRD) for their formation, stability, and crystalline morphology. The UV–Vis spectrum showed a strong peak of surface plasmon resonance at 420 nm, whereas SEM images showed nanoparticles that were spherical and uniformly dispersed with an average size of 28.32 nm, which is an indication of successful nanoparticle synthesis. Assessments based on biological factors showed that the A. excelsa-derived AgNPs are very effective, having an antioxidant activity of 53.19%, a strong α-glucosidase inhibition of 64.42%, and also impressive cytotoxicity of 52.01% against human HepG2 cells, thus confirming their medicinal properties against stress, diabetes, and cancer spread. The indicated anticancer activities are due to the plant-derived bioactive molecules' synergistic interaction which leads to an increase in the generation of reactive oxygen species and consequently the death of cancer cells. With this, A. excelsa-mediated AgNPs become the best choice for a nanoplatform that is easy to produce, biocompatible, and also sustainable for biomedical applications. Future studies need to clarify anticancer mechanisms at the molecular level, perform in vivo safety evaluations, and also look into the translational prospects of these green-synthesized nanoparticles in targeted cancer therapy and drug delivery. The original article has been corrected.
AB - In the original version of this article, the abstract was incorrectly published. The incorrect and the corrected version of the abstract are given below. Incorrect version: The current research work deals with the eco-friendly production of silver nanoparticles (AgNPs) using the aqueous leaf extract of Araucaria excelsa. Furthermore, biomedical significance of AgNPs was assessed particularly in the areas of anticancer, antioxidant, and antidiabetic applications. The adoption of this environmentally friendly technique overcomes the disadvantages of traditional chemical synthesis by employing phytochemicals as the natural reducing and stabilizing agents, thus reducing the toxicity and environmental impact to a great extent. The AgNPs obtained through biosynthesis were characterized by a series of techniques like UV–Vis spectroscopy, FTIR spectroscopy, scanning electron microscopy (SEM), and X-ray diffraction (XRD) for their formation, stability, and crystalline morphology. The UV–Vis spectrum showed a strong peak of surface plasmon resonance at 435.24 nm, whereas SEM images showed nanoparticles that were spherical and uniformly dispersed with an average size of 28.32 nm, which is an indication of successful nanoparticle synthesis. Assessments based on biological factors showed that the A. excelsa-derived AgNPs are very effective, having an antioxidant activity of 78.26%, a strong α-glucosidase inhibition of 65.44%, and also impressive cytotoxicity of 73.22% against human MCF-7 breast cancer cells, thus confirming their medicinal properties against stress, diabetes, and cancer spread. The indicated anticancer activities are due to the plant-derived bioactive molecules’ synergistic interaction which leads to an increase in the generation of reactive oxygen species and consequently the death of cancer cells. With this, A. excelsa-mediated AgNPs become the best choice for a nanoplatform that is easy to produce, biocompatible, and also sustainable for biomedical applications. Future studies are needed to clarify anticancer mechanisms at the molecular level, perform in vivo safety evaluations, and also look into the translational prospects of these green-synthesized nanoparticles in targeted cancer therapy and drug delivery. Corrected version: The current research work deals with the eco-friendly method to produce silver nanoparticles (AgNPs) using the aqueous leaf extract of Araucaria excelsa and furthermore, its biomedical significance, particularly in the areas of anticancer, antioxidant, and antidiabetic applications. The adoption of this environmentally friendly technique overcomes the disadvantages of traditional chemical synthesis by employing phytochemicals as the natural reducing and stabilizing agents, thus reducing the toxicity and environmental impact to a great extent. The AgNPs obtained through biosynthesis were characterized by a series of techniques like UV–Vis spectroscopy, FTIR spectroscopy, scanning electron microscopy (SEM), and X-ray diffraction (XRD) for their formation, stability, and crystalline morphology. The UV–Vis spectrum showed a strong peak of surface plasmon resonance at 420 nm, whereas SEM images showed nanoparticles that were spherical and uniformly dispersed with an average size of 28.32 nm, which is an indication of successful nanoparticle synthesis. Assessments based on biological factors showed that the A. excelsa-derived AgNPs are very effective, having an antioxidant activity of 53.19%, a strong α-glucosidase inhibition of 64.42%, and also impressive cytotoxicity of 52.01% against human HepG2 cells, thus confirming their medicinal properties against stress, diabetes, and cancer spread. The indicated anticancer activities are due to the plant-derived bioactive molecules' synergistic interaction which leads to an increase in the generation of reactive oxygen species and consequently the death of cancer cells. With this, A. excelsa-mediated AgNPs become the best choice for a nanoplatform that is easy to produce, biocompatible, and also sustainable for biomedical applications. Future studies need to clarify anticancer mechanisms at the molecular level, perform in vivo safety evaluations, and also look into the translational prospects of these green-synthesized nanoparticles in targeted cancer therapy and drug delivery. The original article has been corrected.
UR - https://www.scopus.com/pages/publications/105023982806
U2 - 10.1007/s12649-025-03434-6
DO - 10.1007/s12649-025-03434-6
M3 - Comment/debate
AN - SCOPUS:105023982806
SN - 1877-2641
JO - Waste and Biomass Valorization
JF - Waste and Biomass Valorization
ER -