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Comprehensive Analysis of the Therapeutic IgG4 Antibody Pembrolizumab: Hinge Modification Blocks Half Molecule Exchange in Vitro and in Vivo

  • Xiaoyu Yang*
  • , Fengqiang Wang
  • , Ying Zhang
  • , Larry Wang
  • , Svetlana Antonenko
  • , Shuli Zhang
  • , Yi Wei Zhang
  • , Mohammad Tabrizifard
  • , Grigori Ermakov
  • , Derek Wiswell
  • , Maribel Beaumont
  • , Liming Liu
  • , Daisy Richardson
  • , Mohammed Shameem
  • , Alexandre Ambrogelly
  • *Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

38 Scopus citations

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