Comparison of efficacy and safety of fractional CO2 laser versus 70% trichloroacetic acid peel in the treatment of facial freckles and lentigines

Aiman Maqsood*, Fatima Zia, Kiran Irfan, Shehla Shaukat, Ghazala Butt, Ijaz Hussain

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

Objective To Evaluate the efficacy and Safety of Fractional CO2 Laser versus 70% trichloroacetic acid peel in the treatment of facial freckles and lentigines in Asian people of skin type III & IV. Methods A randomized clinical trial, with 92 cases complying with inclusion standards were enrolled. In groups A, 46 patients were treated with fractional CO2 laser. In group B, 46 patients were treated with 70% trichloroacetic acid peel. All the patients were treated and assessed at four weekly intervals for three consecutive sessions by taking photographs. Final results were concluded one month after the last session. Results 92 patients completed the study with mean age of 29±5 years. In group A, 38% patients showed 75% lightening while in Group B, 49% patients showed good response in lesions clearance on face (80-90% lightening). So, the efficacy was significantly higher in patients treated with 70% TCA peel as compared to CO2 laser (p-value≥0.001). Overall percentage reduction in PSI score was higher in group B (64.80%) followed by group A (46.61%). Conclusion 70% TCA was found more efficacious than CO2 laser for pigmented lesions.

Original languageEnglish
Pages (from-to)165-170
Number of pages6
JournalJournal of Pakistan Association of Dermatologists
Volume34
Issue number1
StatePublished - 12 Jan 2024
Externally publishedYes

Bibliographical note

Publisher Copyright:
© 2024 Pakistan Association of Dermatologists. All rights reserved.

Keywords

  • Fractional CO2 laser
  • Freckles
  • Lentigines
  • Trichloroacetic acid

ASJC Scopus subject areas

  • Dermatology

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