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Comparative 13C NMR studies of complexation of imidazolidine-2-selenone and its analogous thione to gold(I) thiomalate

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4 Scopus citations

Abstract

The interaction of gold(I) thiomalate (AuStm)n (Myocrisin) with imidazolidine-2-selenone (SeImt) was studied in an aqueous solution at pH 7.40 using 13C NMR spectroscopy. It was found that SeImt binds more strongly to (AuStm)n than imidazolidine-2-thione and its derivatives as determined by 13C NMR spectroscopy. SeImt reacts differently with Au(Stm)2-, as compared to (AuStm)n. With (AuStm)n, SeImt forms a ternary complex of ImtSe-Au-Strn, releasing free Stm- to solution. Redox reaction of gold(I) to metallic gold and free thiomalate (Stm-) to disulfide (Stm)2 occurs when Au(Stm)2- reacts with SeImt.

Original languageEnglish
Pages (from-to)21-31
Number of pages11
JournalJournal of Coordination Chemistry
Volume39
Issue number1
DOIs
StatePublished - 1996

Bibliographical note

Funding Information:
This research was supported by the KFUPM Research Committee under Project No. CY/DRUG/124.

Keywords

  • Gold
  • Selenone
  • Thiomalate
  • Thione
  • nm

ASJC Scopus subject areas

  • Physical and Theoretical Chemistry
  • Materials Chemistry

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