Co-precipitated vanadium oxide-doped carbon spheres and graphene oxide nanorods serve as antimicrobial and catalytic agents: In silico molecular docking study

Muhammad Ikram*, Muhammad Shahid Ali, Ali Haider, Iram Shahzadi, Muhammad Mustajab, Anwar Ul-Hamid, Anum Shahzadi, Walid Nabgan, Mohammed M. Algaradah, Ahmed M. Fouda, Salamat Ali

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

Undoped V2O5 is characterized by a small surface area and rapid electron-hole recombination, thus rendering it ineffective as a catalytic and antimicrobial agent. In this study, co-precipitation was employed to synthesize vanadium oxide (V2O5) and carbon spheres (CS) followed by doping with specific concentrations (3 and 6 wt%) of graphene oxide (GO) to produce GO/CS-doped V2O5 nanorods (NRs). The enhancement in catalytic and antibacterial activity provided by GO/CS-doped V2O5 was utilized to treat wastewater more efficiently. XRD analysis validated the orthorhombic and tetragonal structure of the synthesized samples. The polycrystalline nature of V2O5 was shown by vibrant circular rings in selected area electron diffraction (SAED) micrographs. TEM analysis endorsed formation of NRs, whereas UV–vis, luminescence (PL) and fourier transform infrared spectroscopy (FTIR), probed the absorption and emission along with stretching and bending vibrations in V-O-V bond. The chemically synthesized NRs exhibited excellent catalytic activity (93.71%) against rhodamine B (RhB) dye in the vicinity of NaBH4. In addition, NRs were used to evaluate in-vitro antimicrobial efficiency of 3.75 mmfor Escherichia coli (E. coli) using inhibition zone measurement. Docking investigations of GO/CS-V2O5 NRs for FabH and FabI of E. coli suggested suppression of above-mentioned enzymes as a possible mechanism. These findings demonstrate that (3 and 6 wt%) GO/CS-V2O5 possessed ample potency for industrial dye degradation and antimicrobial activity.

Original languageEnglish
Article number171045
JournalJournal of Alloys and Compounds
Volume961
DOIs
StatePublished - 25 Oct 2023

Bibliographical note

Publisher Copyright:
© 2023 The Authors

Keywords

  • Antimicrobial activity
  • Co-precipitation
  • Molecular docking analysis
  • Rhodamine B degradation
  • Vanadium oxide

ASJC Scopus subject areas

  • Mechanics of Materials
  • Mechanical Engineering
  • Metals and Alloys
  • Materials Chemistry

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