Characterization of biogenic hydroxyapatite derived from animal bones for biomedical applications

  • S. Ramesh*
  • , Z. Z. Loo
  • , C. Y. Tan
  • , W. J.Kelvin Chew
  • , Y. C. Ching
  • , F. Tarlochan
  • , Hari Chandran
  • , S. Krishnasamy
  • , L. T. Bang
  • , Ahmed A.D. Sarhan
  • *Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

135 Scopus citations

Abstract

In this work, the viability of producing biogenic hydroxyapatite from bio-waste animal bones, namely bovine (cow), caprine (goat) and galline (chicken), through a heat treatment process has been investigated. The animal bones were locally sourced, cleaned to remove collagen and subsequently heat treated in air atmosphere at different temperatures ranging from 600 °C to 1000 °C. From the range of sintering temperatures investigated, it was found that hydroxyapatite derived from bovine bone showed good thermal stability while those produced from caprine and galline bones exhibited phase instability with traces of tri-calcium phosphate (TCP) being detected after heat treatment beyond 700 °C. The porous nature of the bone samples can be observed from the microstructures obtained and supported by low relative density. Heating the bovine and caprine bones at selected temperatures yielded porous HA body, having hardness values that are comparable with human cortical bone. However, the sintered galline bone sample showed higher porosity levels and low hardness when compared to the other two bone types.

Original languageEnglish
Pages (from-to)10525-10530
Number of pages6
JournalCeramics International
Volume44
Issue number9
DOIs
StatePublished - 15 Jun 2018

Bibliographical note

Publisher Copyright:
© 2018 Elsevier Ltd and Techna Group S.r.l.

Keywords

  • Animal bones
  • Heat treatment
  • Hydroxyapatite
  • Microstructure
  • Phase analysis
  • Vickers hardness

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Process Chemistry and Technology
  • Surfaces, Coatings and Films
  • Materials Chemistry

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