Catalytic performance and antibacterial behaviour with molecular docking analysis of silver and polyacrylic acid doped graphene quantum dots

Tahreem Aziz, Muhammad Imran, Ali Haider, Anum Shahzadi, Muhammad Zain Ul Abidin, Anwar Ul-Hamid*, Walid Nabgan*, Mohammed M. Algaradah, Ahmed M. Fouda, Muhammad Ikram*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

In this research, a fixed concentration (3 wt%) of Ag/PAA and PAA/Ag doped graphene quantum dots (GQDs) were synthesized using the co-precipitation technique. A variety of characterization techniques were employed to synthesize samples to investigate their optical, morphological, structural, and compositional analyses, antimicrobial efficacy, and dye degradation potential with molecular docking analysis. GQDs have high solubility, narrow band gaps, and are suitable for electron acceptors and donors but show less adsorption and catalytic behavior. Incorporating polyacrylic acid (PAA) into GQDs increases the catalytic and antibacterial activities due to the carboxylic group (-COOH). Furthermore, introducing silver (Ag) increased the degradation of dye and microbes as it had a high surface-to-volume ratio. In addition, molecular docking studies were used to decipher the mechanism underlying the bactericidal action of silver and polyacrylic acid-doped graphene quantum dots and revealed inhibition of β-lactamase and DNA gyrase.

Original languageEnglish
Pages (from-to)28008-28020
Number of pages13
JournalRSC Advances
Volume13
Issue number40
DOIs
StatePublished - 21 Sep 2023

Bibliographical note

Publisher Copyright:
© 2023 The Royal Society of Chemistry.

ASJC Scopus subject areas

  • General Chemistry
  • General Chemical Engineering

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