Catalytic evaluation and in vitro bacterial inactivation of graphitic carbon nitride/carbon sphere doped bismuth oxide quantum dots with evidential in silico analysis

Muhammad Ikram*, Muhammad Shazaib, Ali Haider, Anum Shahzadi, Shair Baz, Mohammed M. Algaradah, Anwar Ul-Hamid*, Walid Nabgan*, Hisham S.M. Abd-Rabboh, Salamat Ali

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

Herein, Bi2O3 quantum dots (QDs) have been synthesized and doped with various concentrations of graphitic carbon nitride (g-C3N4) and a fixed amount of carbon spheres (CS) using a co-precipitation technique. XRD analysis confirmed the presence of monoclinic structure along the space group P21/c and C2/c. Various functional groups and characteristic peaks of (Bi-O) were identified using FTIR spectra. QDs morphology of Bi2O3 showed agglomeration with higher amounts of g-C3N4 by TEM analysis. HR-TEM determined the variation in the d-spacing which increased with increasing dopants. These doping agents were employed to reduce the exciting recombination rate of Bi2O3 QDs by providing more active sites which enhance antibacterial activity. Notably, (6 wt%) g-C3N4/CS-doped Bi2O3 exhibited considerable antimicrobial potential in opposition to E. coli at higher values of concentrations relative to ciprofloxacin. The (3 wt%) g-C3N4/CS-doped Bi2O3 exhibits the highest catalytic potential (97.67%) against RhB in a neutral medium. The compound g-C3N4/CS-Bi2O3 has been suggested as a potential inhibitor of β-lactamaseE. coli and DNA gyraseE. coli based on the findings of a molecular docking study that was in better agreement with in vitro bactericidal activity.

Original languageEnglish
Pages (from-to)25305-25315
Number of pages11
JournalRSC Advances
Volume13
Issue number36
DOIs
StatePublished - 23 Aug 2023

Bibliographical note

Publisher Copyright:
© 2023 The Royal Society of Chemistry.

ASJC Scopus subject areas

  • General Chemistry
  • General Chemical Engineering

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