Carbon dots support for preconcentration and analysis of anti-inflammatory drug ibuprofen: an innovative remedy for wastewater treatment

Sameera Shafi*, Saba Zafar, Abdullah Aitani, Lamia Fatima, Zaryab Hassan, Awais Ahmad, Saadat Majeed*, Zohaib Sarwar

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

Ibuprofen, an anti-inflammatory medicine, has attracted attention as an emerging environmental pollutant due to its high human consumption, ubiquitous presence in various habitats, and low rate of environmental degradation. Consequently, various types of quantum dots and analytical techniques have been utilized to detect ibuprofen. Nevertheless, these methods often pose toxicity risks and require advanced technical expertise. In this study, fluorescine modified carbon dots (F@CDs) were synthesized from a green precursor, namely milk doped with fluorescein. The resulting F@CDs acted as adsorbent sites, enabling the detection of ibuprofen through analyte adsorption. The findings were quantified using a UV spectrophotometer, while the quenching behavior was observed using a fluorescent lamp. To facilitate convenient and on-site detection of ibuprofen, the F@CDs were preconcentrated on paper-based handmade strips. These synthesized carbon dots exhibited yellowish-green fluorescence, serving as effective probes for detecting ibuprofen in aqueous solutions, even at concentrations as low as 0.193µg/L. This method proxves to be practical by virtue of its simplicity, affordability, ease of use, and environmentally friendly features, coupled with a notable limit of detection.

Original languageEnglish
Pages (from-to)5621-5634
Number of pages14
JournalClean Technologies and Environmental Policy
Volume27
Issue number10
DOIs
StatePublished - Oct 2025

Bibliographical note

Publisher Copyright:
© The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature 2024.

Keywords

  • Anti-inflammatory drug
  • Drug monitoring
  • Fluorescein-doped carbon dots
  • Ibuprofen (IBU)
  • Nanoparticles
  • Paper-based sensing
  • Spectrophotometer
  • Trace analysis

ASJC Scopus subject areas

  • Environmental Engineering
  • Environmental Chemistry
  • General Business, Management and Accounting
  • Economics and Econometrics
  • Management, Monitoring, Policy and Law

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