Automation of compartmental electrophoresis apparatus for the separation of non-covalently attached polysaccharides from proteins

Ahsan Mushir Shemsi, Tanvir Ahmad, Muhammad Hamid Rashid, Khawar Sohail Siddiqui*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

We have improved the design of compartmental electrophoresis apparatus. Gel casting has been made very quickly and simply by employing perspex plugs which screw into wax casting cylinders. The apparatus has been automated by connecting an electronic circuitry to a peristaltic pump which keeps the levels and pH of buffers constant in anodic and cathodic chambers. A water jacket has also been added to the apparatus. This vastly improved version of compartmental electrophoresis apparatus could now be successfully used for the separation of noncovalently linked polysaccharides from any protein or enzyme.

Original languageEnglish
Pages (from-to)76-77
Number of pages2
JournalEnzyme and Microbial Technology
Volume22
Issue number1
DOIs
StatePublished - 1 Jan 1998
Externally publishedYes

Bibliographical note

Funding Information:
We wish to acknowledge the NIBGE Director Dr. Kauser A. Malik for providing research facilities. We are very grateful to NIAB Senior Engineer, Mr. M. Shaukat for fabricating the apparatus. The valuable suggestions of Mr. M.A. Farooqui regarding the design of circuitry are appreciated. This work was financed by PAEC. The technical assistance of G.A. Waseer is also acknowledged.

Keywords

  • Automation
  • Compartmental electrophoresis
  • Electronic circuitry
  • Polysaccharides
  • Proteins

ASJC Scopus subject areas

  • Biotechnology
  • Bioengineering
  • Biochemistry
  • Applied Microbiology and Biotechnology

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