Aptamer biosensor for label-free impedance spectroscopy detection of proteins based on recognition-induced switching of the surface charge

Marcela C. Rodriguez, Abdel Nasser Kawde, Joseph Wang*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

335 Scopus citations

Abstract

The recognition of proteins, by aptamer-modified electrode transducers reverses the surface charge and leads to a novel label-free impedance spectroscopy bioelectronic detection protocol based on a decrease in the electron transfer resistance.

Original languageEnglish
Pages (from-to)4267-4269
Number of pages3
JournalChemical Communications
Issue number34
DOIs
StatePublished - 14 Sep 2005
Externally publishedYes

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Catalysis
  • Ceramics and Composites
  • General Chemistry
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

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