An overview of key industrial product citric acid production by Aspergillus niger and its application

  • Ambreen Latif
  • , Noor Hassan
  • , Hazrat Ali*
  • , Muhammad Bilal Khan Niazi
  • , Zaib Jahan
  • , Iqra Latif Ghuman
  • , Farwa Hassan
  • , Anam Saqib
  • *Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

15 Scopus citations

Abstract

Citric acid possesses high economic value and is considered as the world’s largest consumed organic acid in numerous industries. Citric acid applications range from food to beverage industries, pharmaceuticals, cosmetics, and the environment. It is mostly produced by microbial fermentation, but Aspergillus niger is considered as the main workhorse for large-scale production of citric acid. In the current review, special devotion has been made toward addressing the latest and innovative literature related to production of citric acid by A. niger. The review article discusses A. niger historical involvement in citric acid production, fermentation technologies, molecular biology, biosynthesis, accumulation of citric acid, methods for enhanced production of citric acid, different operational factors also influencing citric acid production, and various techniques used for citric acid recovery. Also, copious biotechnological applications of citric acid are summarized for a fundamental comprehension of the subject and its critical role in diverse fields of industries.

Original languageEnglish
Article numberkuaf007
JournalJournal of Industrial Microbiology and Biotechnology
Volume52
DOIs
StatePublished - 2025

Bibliographical note

Publisher Copyright:
© The Author(s) 2025. Published by Oxford University Press on behalf of Society of Industrial Microbiology and Biotechnology.

Keywords

  • A. niger
  • Citric acid
  • Fermentation
  • Industry
  • Molecular biology

ASJC Scopus subject areas

  • General Medicine

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