Abstract
The NMR spectra of several 1-oxa-11-azabicyclo [6,3,0]undecanes, with substituents at 2 and 3 positions, showed the presence of two isomer s of unequal populations at -50 °C. The major isomer is shown to be the trans conformer which is in equilibrium with a minor isomer (cis conformer) by a relatively slow nitrogen inversion process. The barriers to nitrogen inversion were determined by the NMR band shape analysis and found to be in the range 53.5-57.4 kJ/mol. Syntheses of four new compounds are described.
| Original language | English |
|---|---|
| Pages (from-to) | X-165 |
| Journal | Canadian Journal of Analytical Sciences and Spectroscopy |
| Volume | 42 |
| Issue number | 6 |
| State | Published - 1997 |
Keywords
- 1-oxa-11-azabicyclo[6,3,0]undecanes
- C chemical shifts
- Nitrogen inversion
ASJC Scopus subject areas
- Analytical Chemistry
- Atomic and Molecular Physics, and Optics
- Spectroscopy