A reaction between captopril (a high blood pressure drug) and gold(I)-thiomalate

Anvarhusein A. Isab

doi:10.1016/0162-0134(87)80044-2

A reaction between captopril (a high blood pressure drug) and gold(I)-thiomalate

Anvarhusein A. Isab^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

19 Scopus citations

Abstract

A reaction of gold(I) thiomalates [Au(tm)], "Myocrisin" (an antiarthritic drug), with captopril (a high blood pressure drug) was carried out in aqueous solution at pH^* 7.20 using ¹³c NMR spectroscopy. Captopril, which exists in the cis (c) and trans (t) isomer forms, binds strongly with gold(I), ejecting thiomalate (Htm) as free ligand into solution.

Original language	English
Pages (from-to)	69-75
Number of pages	7
Journal	Journal of Inorganic Biochemistry
Volume	30
Issue number	1
DOIs	https://doi.org/10.1016/0162-0134(87)80044-2
State	Published - May 1987

ASJC Scopus subject areas

Biochemistry
Inorganic Chemistry

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title = "A reaction between captopril (a high blood pressure drug) and gold(I)-thiomalate",

abstract = "A reaction of gold(I) thiomalates [Au(tm)], {"}Myocrisin{"} (an antiarthritic drug), with captopril (a high blood pressure drug) was carried out in aqueous solution at pH* 7.20 using 13c NMR spectroscopy. Captopril, which exists in the cis (c) and trans (t) isomer forms, binds strongly with gold(I), ejecting thiomalate (Htm) as free ligand into solution.",

author = "Isab, \{Anvarhusein A.\}",

year = "1987",

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T1 - A reaction between captopril (a high blood pressure drug) and gold(I)-thiomalate

AU - Isab, Anvarhusein A.

PY - 1987/5

Y1 - 1987/5

N2 - A reaction of gold(I) thiomalates [Au(tm)], "Myocrisin" (an antiarthritic drug), with captopril (a high blood pressure drug) was carried out in aqueous solution at pH* 7.20 using 13c NMR spectroscopy. Captopril, which exists in the cis (c) and trans (t) isomer forms, binds strongly with gold(I), ejecting thiomalate (Htm) as free ligand into solution.

AB - A reaction of gold(I) thiomalates [Au(tm)], "Myocrisin" (an antiarthritic drug), with captopril (a high blood pressure drug) was carried out in aqueous solution at pH* 7.20 using 13c NMR spectroscopy. Captopril, which exists in the cis (c) and trans (t) isomer forms, binds strongly with gold(I), ejecting thiomalate (Htm) as free ligand into solution.

UR - https://www.scopus.com/pages/publications/0023263557

U2 - 10.1016/0162-0134(87)80044-2

DO - 10.1016/0162-0134(87)80044-2

M3 - Article

C2 - 3108454

AN - SCOPUS:0023263557

SN - 0162-0134

VL - 30

SP - 69

EP - 75

JO - Journal of Inorganic Biochemistry

JF - Journal of Inorganic Biochemistry

IS - 1

ER -

A reaction between captopril (a high blood pressure drug) and gold(I)-thiomalate

Abstract

ASJC Scopus subject areas

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