TY - JOUR
T1 - A novel tin-oxide nanoparticle-modified glassy carbon electrode for the highly selective and simultaneous detection of dopamine, uric acid, and ascorbic acid
AU - Awal, Abdul
AU - Ferdaus, Fahima
AU - Hossain, Md Abdul Kabir
AU - Zahir, Md Hasan
AU - Hoque, Mozammal
AU - Hossain, Md Delwar
AU - Al-Qwairi, Fatima Omar
AU - Shah, Syed Shaheen
AU - Aziz, Md Abdul
AU - Ahammad, A. J.Saleh
N1 - Publisher Copyright:
This journal is © The Royal Society of Chemistry and the Centre National de la Recherche Scientifique, 2026
PY - 2026/1/26
Y1 - 2026/1/26
N2 - A novel electrochemical sensor has been developed using tin oxide nanoparticles (SnOxNPs)-modified glassy carbon electrodes (GCEs) for the simultaneous detection of ascorbic acid (AA), dopamine (DA), and uric acid (UA). SnOxNPs were produced by hydrothermal synthesis, and were analyzed using several structural characterization techniques, confirming their nanoscale dimensions and crystalline structure. The electrocatalytic performance of the SnOxNPs–GCE improved due to enhanced electrical conductivity and better interactions at the electrode surface. The enhancement in analytical response stems from well-defined interactions between the analytical compounds and the SnOxNPs–GCE surface during electrochemical measurements. The electrode demonstrated low detection limits of 0.148 µM, 0.544 µM, and 12.56 µM for DA, UA, and AA, respectively. The constructed sensor effectively resisted external interference from substances such as glucose, citric acid, and l-cysteine, as well as urea and metal ions (Na+, Mg2+, and Ca2+). This proposed electrode also exhibits excellent analytical characteristics, including high sensitivity, stability, and reproducibility toward DA, UA, and AA.
AB - A novel electrochemical sensor has been developed using tin oxide nanoparticles (SnOxNPs)-modified glassy carbon electrodes (GCEs) for the simultaneous detection of ascorbic acid (AA), dopamine (DA), and uric acid (UA). SnOxNPs were produced by hydrothermal synthesis, and were analyzed using several structural characterization techniques, confirming their nanoscale dimensions and crystalline structure. The electrocatalytic performance of the SnOxNPs–GCE improved due to enhanced electrical conductivity and better interactions at the electrode surface. The enhancement in analytical response stems from well-defined interactions between the analytical compounds and the SnOxNPs–GCE surface during electrochemical measurements. The electrode demonstrated low detection limits of 0.148 µM, 0.544 µM, and 12.56 µM for DA, UA, and AA, respectively. The constructed sensor effectively resisted external interference from substances such as glucose, citric acid, and l-cysteine, as well as urea and metal ions (Na+, Mg2+, and Ca2+). This proposed electrode also exhibits excellent analytical characteristics, including high sensitivity, stability, and reproducibility toward DA, UA, and AA.
UR - https://www.scopus.com/pages/publications/105026569707
U2 - 10.1039/d5nj03381k
DO - 10.1039/d5nj03381k
M3 - Article
AN - SCOPUS:105026569707
SN - 1144-0546
VL - 50
SP - 1734
EP - 1749
JO - New Journal of Chemistry
JF - New Journal of Chemistry
IS - 4
ER -