A Kinetic Method for the Determination of Carbimazole in Pharmaceutical Preparations by Oxidation with Bichromate in Sulfuric Acid

Salah M. Sultan

doi:10.2116/analsci.8.503

A Kinetic Method for the Determination of Carbimazole in Pharmaceutical Preparations by Oxidation with Bichromate in Sulfuric Acid

Salah M. Sultan^*

^*Corresponding author for this work

King Fahd University of Petroleum & Minerals

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

A simple spectrophotometric method is introduced for the determination of Carbimazole in drug formulation. The method requires the use of 16 mg ml^-1 potassium dichromate, 0.5 M sulfuric acid and heating at 90° C for 25 min. The method is easily applied to the determination of Carbimazole in tablet formulations. The accuracy of the method was tested by a statistical comparison with the British Pharmacopeia official method.

Original language	English
Pages (from-to)	503-506
Number of pages	4
Journal	Analytical Sciences
Volume	8
Issue number	4
DOIs	https://doi.org/10.2116/analsci.8.503
State	Published - 1992

Keywords

Carbimazole
fixed time method
kinetics
potassium dichromate
spectrophotometry

ASJC Scopus subject areas

Analytical Chemistry

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10.2116/analsci.8.503

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title = "A Kinetic Method for the Determination of Carbimazole in Pharmaceutical Preparations by Oxidation with Bichromate in Sulfuric Acid",

abstract = "A simple spectrophotometric method is introduced for the determination of Carbimazole in drug formulation. The method requires the use of 16 mg ml-1 potassium dichromate, 0.5 M sulfuric acid and heating at 90° C for 25 min. The method is easily applied to the determination of Carbimazole in tablet formulations. The accuracy of the method was tested by a statistical comparison with the British Pharmacopeia official method.",

keywords = "Carbimazole, fixed time method, kinetics, potassium dichromate, spectrophotometry",

author = "Sultan, \{Salah M.\}",

year = "1992",

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pages = "503--506",

journal = "Analytical Sciences",

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AU - Sultan, Salah M.

PY - 1992

Y1 - 1992

N2 - A simple spectrophotometric method is introduced for the determination of Carbimazole in drug formulation. The method requires the use of 16 mg ml-1 potassium dichromate, 0.5 M sulfuric acid and heating at 90° C for 25 min. The method is easily applied to the determination of Carbimazole in tablet formulations. The accuracy of the method was tested by a statistical comparison with the British Pharmacopeia official method.

AB - A simple spectrophotometric method is introduced for the determination of Carbimazole in drug formulation. The method requires the use of 16 mg ml-1 potassium dichromate, 0.5 M sulfuric acid and heating at 90° C for 25 min. The method is easily applied to the determination of Carbimazole in tablet formulations. The accuracy of the method was tested by a statistical comparison with the British Pharmacopeia official method.

KW - Carbimazole

KW - fixed time method

KW - kinetics

KW - potassium dichromate

KW - spectrophotometry

UR - https://www.scopus.com/pages/publications/85004208900

U2 - 10.2116/analsci.8.503

DO - 10.2116/analsci.8.503

M3 - Article

AN - SCOPUS:85004208900

SN - 0910-6340

VL - 8

SP - 503

EP - 506

JO - Analytical Sciences

JF - Analytical Sciences

IS - 4

ER -

A Kinetic Method for the Determination of Carbimazole in Pharmaceutical Preparations by Oxidation with Bichromate in Sulfuric Acid

Abstract

Keywords

ASJC Scopus subject areas

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