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A disposable glucose biosensor based on diffusional mediator dispersed in nanoparticulate membrane on screen-printed carbon electrode

  • Z. Gao*
  • , F. Xie
  • , M. S.M. Arshad
  • , J. Y. Ying
  • *Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

A disposable glucose biosensor based on co-dispersion of a divisional polymeric mediator and glucose oxidase (GOX) in nanoparticulate membrane on screen-printed carbon electrode was described. The biosensor exhibited classical features of a kinetically fast redox couple. At scan rates up to 200 mV/s, the peak-to-peak potential separation of the mediator was 59 mV at 25°C. In the presence of glucose, a typical catalytic oxidation current was observed, which reached a plateau at 0.30 V (vs. Ag/AgCl). Amperometric peak current at 5 s and the subsequent currents at longer test times were linear to the glucose concentration in the range of 5 to 600 mg/dl. By constructing a miniature channel on the screen-printed electrode and partially filling the channel with the nanoparticulate sensing membrane, glucose can be accurately determined in as little as 0.20 μl of sample. Successful attempts were made in blood sugar analysis.

Original languageEnglish
Title of host publication2004 NSTI Nanotechnology Conference and Trade Show - NSTI Nanotech 2004
EditorsM. Laudon, B. Romanowicz
Pages209-212
Number of pages4
StatePublished - 2004
Externally publishedYes

Publication series

Name2004 NSTI Nanotechnology Conference and Trade Show - NSTI Nanotech 2004
Volume1

Keywords

  • Biosensors
  • Ferrocene
  • Glucose
  • Glucose oxidase
  • Nanoparticles

ASJC Scopus subject areas

  • General Engineering

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