A critical review on the synthesis of natural sodium alginate based composite materials: An innovative biological polymer for biomedical delivery applications

Awais Ahmad; N. M. Mubarak; Fakiha Tul Jannat; Tayyaba Ashfaq; Carlo Santulli; Muhammad Rizwan; Agnieszka Najda; May Bin-Jumah; Mohamed M. Abdel-Daim; Shahid Hussain; Shafaqat Ali

doi:10.3390/pr9010137

A critical review on the synthesis of natural sodium alginate based composite materials: An innovative biological polymer for biomedical delivery applications

Awais Ahmad
, N. M. Mubarak
, Fakiha Tul Jannat
, Tayyaba Ashfaq
, Carlo Santulli
, Muhammad Rizwan
, Agnieszka Najda^*
, May Bin-Jumah
, Mohamed M. Abdel-Daim
, Shahid Hussain^*
, Shafaqat Ali^*

^*Corresponding author for this work

Research output: Contribution to journal › Review article › peer-review

159 Scopus citations

Abstract

Sodium alginate (Na-Alg) is water-soluble, neutral, and linear polysaccharide. It is the derivative of alginic acid which comprises 1,4-β-d-mannuronic (M) and α-l-guluronic (G) acids and has the chemical formula (NaC₆H₇O₆). It shows water-soluble, non-toxic, biocompatible, biodegradable, and non-immunogenic properties. It had been used for various biomedical applications, among which the most promising are drug delivery, gene delivery, wound dressing, and wound healing. For different biomedical applications, it is used in different forms with the help of new techniques. That is the reason it had been blended with different polymers. In this review article, we present a comprehensive overview of the combinations of sodium alginate with natural and synthetic polymers and their biomedical applications involving delivery systems. All the scientific/technical issues have been addressed, and we have highlighted the recent advancements.

Original language	English
Article number	137
Pages (from-to)	1-27
Number of pages	27
Journal	Processes
Volume	9
Issue number	1
DOIs	https://doi.org/10.3390/pr9010137
State	Published - 1 Jan 2021
Externally published	Yes

Bibliographical note

Publisher Copyright:
© 2021 by the authors. Licensee MDPI, Basel, Switzerland.

Keywords

Biomedical application
Biomedical delivery
Gene delivery
Natural polymer
Sodium alginate

ASJC Scopus subject areas

Bioengineering
Chemical Engineering (miscellaneous)
Process Chemistry and Technology

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10.3390/pr9010137

Cite this

Ahmad, A., Mubarak, N. M., Jannat, F. T., Ashfaq, T., Santulli, C., Rizwan, M., Najda, A., Bin-Jumah, M., Abdel-Daim, M. M., Hussain, S., & Ali, S. (2021). A critical review on the synthesis of natural sodium alginate based composite materials: An innovative biological polymer for biomedical delivery applications. Processes, 9(1), 1-27. Article 137. https://doi.org/10.3390/pr9010137

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title = "A critical review on the synthesis of natural sodium alginate based composite materials: An innovative biological polymer for biomedical delivery applications",

abstract = "Sodium alginate (Na-Alg) is water-soluble, neutral, and linear polysaccharide. It is the derivative of alginic acid which comprises 1,4-β-d-mannuronic (M) and α-l-guluronic (G) acids and has the chemical formula (NaC6H7O6). It shows water-soluble, non-toxic, biocompatible, biodegradable, and non-immunogenic properties. It had been used for various biomedical applications, among which the most promising are drug delivery, gene delivery, wound dressing, and wound healing. For different biomedical applications, it is used in different forms with the help of new techniques. That is the reason it had been blended with different polymers. In this review article, we present a comprehensive overview of the combinations of sodium alginate with natural and synthetic polymers and their biomedical applications involving delivery systems. All the scientific/technical issues have been addressed, and we have highlighted the recent advancements.",

keywords = "Biomedical application, Biomedical delivery, Gene delivery, Natural polymer, Sodium alginate",

author = "Awais Ahmad and Mubarak, \{N. M.\} and Jannat, \{Fakiha Tul\} and Tayyaba Ashfaq and Carlo Santulli and Muhammad Rizwan and Agnieszka Najda and May Bin-Jumah and Abdel-Daim, \{Mohamed M.\} and Shahid Hussain and Shafaqat Ali",

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Ahmad, A, Mubarak, NM, Jannat, FT, Ashfaq, T, Santulli, C, Rizwan, M, Najda, A, Bin-Jumah, M, Abdel-Daim, MM, Hussain, S & Ali, S 2021, 'A critical review on the synthesis of natural sodium alginate based composite materials: An innovative biological polymer for biomedical delivery applications', Processes, vol. 9, no. 1, 137, pp. 1-27. https://doi.org/10.3390/pr9010137

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T1 - A critical review on the synthesis of natural sodium alginate based composite materials

T2 - An innovative biological polymer for biomedical delivery applications

AU - Ahmad, Awais

AU - Mubarak, N. M.

AU - Jannat, Fakiha Tul

AU - Ashfaq, Tayyaba

AU - Santulli, Carlo

AU - Rizwan, Muhammad

AU - Najda, Agnieszka

AU - Bin-Jumah, May

AU - Abdel-Daim, Mohamed M.

AU - Hussain, Shahid

AU - Ali, Shafaqat

PY - 2021/1/1

Y1 - 2021/1/1

N2 - Sodium alginate (Na-Alg) is water-soluble, neutral, and linear polysaccharide. It is the derivative of alginic acid which comprises 1,4-β-d-mannuronic (M) and α-l-guluronic (G) acids and has the chemical formula (NaC6H7O6). It shows water-soluble, non-toxic, biocompatible, biodegradable, and non-immunogenic properties. It had been used for various biomedical applications, among which the most promising are drug delivery, gene delivery, wound dressing, and wound healing. For different biomedical applications, it is used in different forms with the help of new techniques. That is the reason it had been blended with different polymers. In this review article, we present a comprehensive overview of the combinations of sodium alginate with natural and synthetic polymers and their biomedical applications involving delivery systems. All the scientific/technical issues have been addressed, and we have highlighted the recent advancements.

AB - Sodium alginate (Na-Alg) is water-soluble, neutral, and linear polysaccharide. It is the derivative of alginic acid which comprises 1,4-β-d-mannuronic (M) and α-l-guluronic (G) acids and has the chemical formula (NaC6H7O6). It shows water-soluble, non-toxic, biocompatible, biodegradable, and non-immunogenic properties. It had been used for various biomedical applications, among which the most promising are drug delivery, gene delivery, wound dressing, and wound healing. For different biomedical applications, it is used in different forms with the help of new techniques. That is the reason it had been blended with different polymers. In this review article, we present a comprehensive overview of the combinations of sodium alginate with natural and synthetic polymers and their biomedical applications involving delivery systems. All the scientific/technical issues have been addressed, and we have highlighted the recent advancements.

KW - Biomedical application

KW - Biomedical delivery

KW - Gene delivery

KW - Natural polymer

KW - Sodium alginate

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DO - 10.3390/pr9010137

M3 - Review article

AN - SCOPUS:85099970324

SN - 2227-9717

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JO - Processes

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IS - 1

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ER -

A critical review on the synthesis of natural sodium alginate based composite materials: An innovative biological polymer for biomedical delivery applications

Abstract

Bibliographical note

Keywords

ASJC Scopus subject areas

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